Assessment of Capsule Related Antibiotic Resistance of Pseudomonas aeruginosa Isolated from Patients Attending some Hospitals in Kano State, Nigeria

Resistance to antimicrobial substances by pathogenic microorganisms is on the rise since beginning of modern medicine. Mechanisms; enzymatic degradation, loss target and interception are employed bacteria in resisting antimicrobials. Bacterial capsule a gelatinous outer layer surrounding bacterial cell composed primarily polysaccharide. This study assessed role that Pseudomonas aeruginosa played carbapenem resistance. P. was isolated from 49 (16%) samples out 300 screened. India ink staining technique used detect capsule. Capsule detected 42 (86%) isolates whereas 7 (14%) were non-capsulated. All capsulated strains resistant antibiotics (Meropenem, Doripenem Imipenem) non-capsulated susceptible antibiotics. The results this however suggest involvement resistance employed.